• 목록
• 답변
• 게시판 리스트 옵션
  • 수정
  • 삭제

Khandaker Md. Sharif Uddin ImamKhandaker Md. More by Khandaker Md. Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days. Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts. The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Find more information on the Altmetric Attention Score and how the score is calculated. Lentinula edodes (Berk.), commonly known as "shiitake mushroom", is one of the most popular species of cultivated edible mushrooms (22% of the world’s production). In addition to its culinary popularity, L. edodes is also praised for its nutraceutical and medicinal use as an immunomodulatory, antioxidant, hypolipidemic, hepatoprotective, anti-inflammatory, antitumor, and anticancer agent. Cancer is currently the leading cause of death worldwide, and lung cancers, especially adenocarcinomas (75-85% of all lung cancers), make the largest contribution to this number.

Investigating edible and potentially medicinal mushrooms like L. edodes may lead to the discovery of prospective anticancer agents. Here we extracted the shiitake QF808-1 strain, a popular variety of L. edodes from China, using five solvents. Among the samples, the aqueous extract had the highest number of metabolites while exerting dose-dependent bioactivity by inhibiting A549 lung adenocarcinoma cell proliferation, with a half-maximal inhibitory concentration (IC50) of 198.5 μg/mL. Further bioactivity-guided fractionation of the aqueous extract through silica gel column chromatography and semipreparative high-performance liquid chromatography resulted in the isolation of 10 cytotoxic isolates. Comparative cytotoxicity analysis of the isolates showed their IC50 values against A549 cells ranged from 55.03 to 721.14 μg/mL. Identification of the most cytotoxic isolate by UHPLC-Orbitrap mass spectrometry and one-dimensional nuclear magnetic resonance revealed it as indole-3-lactic acid (ILA). Our findings provided evidence of potential anticancer metabolites, including ILA in aqueous extract of L. edodes, and suggested its prospective use in cancer treatment. To access this article, please review the available access options below.

Read this article for 48 hours. Check out below using your ACS ID or as a guest. You may have access to this article through your institution. Your institution does not have access to this content. You can change your affiliated institution below. You may have access to this article with your ACS ID if you have previously purchased it or have ACS member benefits. Most electronic Supporting Information files are available without a subscription to ACS Web Editions. Such files may be downloaded by article for research use (if there is a public use license linked to the relevant article, that license may permit other uses). This article is cited by 5 publications. Kashif Ameer, Maruf Ahmed, Mian Anjum Murtaza, Shahida Anusha Siddiqui. Lentinula edodes (Berk.) Pegler. Ishtiaq Ahmad, Maryum Arif, Mimi Xu, Jianyou Zhang, Yuting Ding, Fei Lyu. Therapeutic values and nutraceutical properties of shiitake mushroom (Lentinula edodes): A review. Marília Aparecida Fidelis e Moura, Bruna de Almeida Martins, Geane P. de Oliveira, Jacqueline A. Takahashi. Alternative protein sources of plant, algal, fungal and insect origins for dietary diversification in search of nutrition and health. Shaza M. Elhusseiny, Taghrid S. El-Mahdy, Mohamed F. Awad, Nooran S. Elleboudy, Mohamed M. S. Farag, Mahmoud A. Yassein, Khaled M. Aboshanab. Proteome Analysis and In Vitro Antiviral, Anticancer and Antioxidant Capacities of the Aqueous Extracts of Lentinula edodes and Pleurotus ostreatus Edible Mushrooms. In case you have almost any inquiries with regards to wherever as well as the way to utilize manufacturer of shiitake mushroom extract powder as Raw Material for pharmaceuticals, you are able to contact us with our own site. Marek Siwulski, Anna Budka, Sylwia Budzyńska, Monika Gąsecka, Pavel Kalač, Przemysław Niedzielski, Mirosław Mleczek. Mineral composition of traditional and organic-cultivated mushroom Lentinula edodes in Europe and Asia - Similar or different?

Published: Mar 1, 2022 · Modified: Aug 24, 2022 by Mrs. Mushroom · This post may contain affiliate links · What comes to mind when you think of shiitake mushrooms? Do you ponder how the health benefits can improve your life? Do you ruminate upon beautiful fungi sprouting in a warm hardwood forest? Maybe you just think about your favorite dish at the local Chinese restaurant. Any of these scenarios can apply, as shiitake is one of the most versatile mushrooms out there! It’s a powerful medicinal, an extremely popular cultivation choice, and just plain delicious. You may not be able to tell a lion’s mane from a chanterelle, but chances are you’ve heard of shiitake. Let’s learn more about the shiitake mushroom, Lentinula edodes. We’ll start with some basic facts, and then move on to their medicinal properties. We’ll finish with what’s on everyone’s mind, how to cook them.

At the bottom of this page is an easy shiitake mushroom recipe. Hopefully by the time you finish this article, you’ll be eager to try it out! Shiitake goes by many different names. The Latin name is Lentinula edodes, although in English they’re sometimes known as black forest mushrooms or Chinese black mushrooms. The name shiitake is Japanese, meaning "shii mushroom". Shiitake begin their lives with dark brown to black caps, which become lighter brown and more convex with age. The undersides sport white gills that do not attach to the stem. The spore print is white. The stem (or stipe) of the mushroom is smooth, fibrous, and light brown with no ring. If you damage the stem, it will bruise a deeper brownish color. Shiitake mushrooms grow in the Far East, mainly Japan, China, and Korea. They fruit from spring to late summer or early fall. This species is a true saprotroph, meaning they feed on dead tissue.